The AAPS Journal - Themed Issue

NIDA/AAPS Symposium on Drugs of Abuse: Mechanisms of Toxicity, Toxicokinetics and Medical Consequences, November 4-5, 2005
Guest Editors: Rao S. Rapaka and Jagitsing H. Khalsa

Table of Contents

Cytochrome P450s and Other Enzymes in Drug Metabolism and Toxicity
F. Peter Guengerich

Causes and Consequences of Methamphetamine and MDMA Toxicity
Maria S. Quinton and Bryan K. Yamamoto

Mechanisms of Methamphetamine-induced Dopaminergic Neurotoxicity
Evan L. Riddle, Annette E. Fleckenstein, and Glen R. Hanson

Developmental Toxicity of Prenatal Exposure to Toluene
Scott E. Bowen and John H. Hannigan

Endocannabinoid Signaling Directs Periimplantation Events
Haibin Wang, Huirong Xie, and Sudhansu K. Dey

MicroPET Investigation of Chronic Long-Term Neurotoxicity from Heavy Ion Irradiation
Onarae Rice, Sandra Saintvictor, Michael Michaelides, Panayotis Thanos, and Samuel John Gatley

Mitochondria-Targeted Peptide Antioxidants: Novel Neuroprotective Agents
Hazel H. Szeto

NAD Metabolism and Sirtuins: Metabolic Regulation of Protein Deacetylation in Stress and Toxicity
Tianle Yang and Anthony A. Sauve

Vesicular Monoamine Transporter 2: Role as a Novel Target for Drug Development
Zheng G, Dwoskin LP, Crooks PA

Quantitative Determination of Total Methamphetamine and Active Metabolites in Rat Tissue by Liquid Chromatography With Tandem Mass Spectrometric Detection
Howard Hendrickson, Elizabeth Laurenzana, S. Michael Owens